There is a lot of confusion around ‘methyl group’, ‘methyl donor’, ‘methylation’.
I’ve created a quick cheat sheet here for you.
- Carbon + 3 hydrogens (CH3)
- The act of giving a methyl group to another compound altering its chemical structure thereby changing it to something else. This is a carefully orchestrated transfer from one compound to another which requires an enzymatic process.
- Uracil + CH3 = Thymine
- Dopamine + CH3 = Norepinephrine
- Guanidoacetate + CH3 = Creatine
Not Methyl groups (rumors)
- CoQ10 (any type)
- When methylfolate and methylcobalamin cannot join forces and meet together.
- This is typically caused by ‘methyl blocking’ or a deficiency of one or the other (methylfolate or methylcobalamin)
- This can falsely elevate serum folate and/or serum cobalamin
There you have it.
It is really that simple.
Did I miss any? Are you wondering if ‘X’ or ‘Y’ is a methyl donor? Comment below and I’ll review it and then add it to the appropriate list.