Vitamin D, Infections and Chronic Disease

Blog, Featured, Uncategorized 109 Comments

A normal vitamin D level means little.

We think bacteria and viruses are tiny little things we can easily eliminate. Sometimes yes. Other times – far from. They are smart. They have evolved with us and also way faster than us.

Why?

Turns out that these little punks (infections) hijack our ability to USE vitamin D for our immune system.
Because they know that vitamin D kills them.
 
Next time you go to the doctor, check your 25 OH vitamin D3, don’t think you’re ‘Great! Your levels are above 50’ – no.
 
That’s not how it works.
 
I highly recommend you talk with your doctor about checking your 25 OH Vitamin D3 AND 1,25 OH Vitamin D3 levels.
 
It is the 1,25 OH Vitamin D3 that is the active one.
 
However, that still isn’t enough because what that active vitamin D3 does is stimulate your vitamin D gene to get to work fighting infections.
 
Issue?
 
Some of infections can block your vitamin D gene from working!
 

If you’ve struggled for a long time, you MUST look for infections.

  • chronic pain
  • chronic fatigue
  • mental dysfunction / mood swings
  • autoimmune conditions
  • chronic stress
You MUST look for infections.
 
Any type of infection you must look for:
  • Lyme
  • Mold
  • Viral
  • Bacterial
  • STD
  • Parasite
 
All locations should be evaluated:
  • Nose and Sinus (swab – culture and sensitivity and possible x-ray)
  • Teeth and Gums (swab and possible x-ray)
  • Blood
  • Urine
  • Stool (comprehensive digestive stool analysis)

Bottom Line:

Having a ‘normal’ 25 OH Vitamin D3 level is NOT enough.

Is your 25 OH Vitamin D3 level above normal but feeling abnormal?
Has your doctor checked for chronic infections?
Comment below and share your experience.

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Comments 109

  1. I have two chronic infections. Vitamin D keeps dipping, last time to 11.5. Something happened to my gut ten years ago. My mother was in the hospital and I was there with her daily for over a month. It started then. I had lots of acid and used omniprizole. It calmed for a while and then riled up with a vengeance a few months later. It was as if I was full of acid and acid was flowing from me. Nothing touched it. Now, I’ve become sensitive to wheat, gluten and egg whites. I seem to not absorb nutrients normally. I am now diagnosed Hashimoto’s. I think I’ll request a comprehensive digestive analysis next doctor visit.

  2. I have two chronic infections. Vitamin D keeps dipping, last time to 11.5. Something happened to my gut ten years ago. My mother was in the hospital and I was there with her daily for over a month. It started then. I had lots of acid and used omniprizole. It calmed for a while and then riled up with a vengeance a few months later. It was as if I was full of acid and acid was flowing from me. Nothing touched it. Now, I’ve become sensitive to wheat, gluten and egg whites. I seem to not absorb nutrients normally. I am now diagnosed Hashimoto’s. I think I’ll request a comprehensive digestive analysis next doctor visit.

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  3. I agree 100% and know this to be true in myself. My Vit D3 was perfect, but I was still sick until I treated mold, viruses, parasites, h pylori and I’m sure I hit others like blastocystis hominis. I keep struggling with something so I’m going to revisit viruses and MARCoNS. Thanks for this info! I got this!!

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      Yeah you do! Thanks for sharing! Exactly my points! Go get them bugs! Key is to also sleep well, eat well, plug into nature, community, etc – lower that stress – or the bugs will just come right back. You sound super positive so I’ve no doubt you’ll move through!

  4. I agree 100% and know this to be true in myself. My Vit D3 was perfect, but I was still sick until I treated mold, viruses, parasites, h pylori and I’m sure I hit others like blastocystis hominis. I keep struggling with something so I’m going to revisit viruses and MARCoNS. Thanks for this info! I got this!!

  5. Do you recommend supplementing with D3 if you are genetic VDR neg? Does it always depend on your blood levels of the D components?

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      Depends on presence of chronic infection or not. I am learning that one should reduce vitamin D during a chronic infection as it works better to kill it this way. Learning this from Shawn Bean and Lesley Fein, MD. I’ve a ways to go yet. Basing vitamin D supplementation on a SNP is not advisable.

      1. Dr Fein is amazing. The absolute best aam brightest. I am so glad I am her patient and that I get to benefit from her vast knowledge. She is a true lifesaver.

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          Awesome! I look forward to learning from her more. I’ve a long ways to go! Please tell her I look forward to following up here sometime this summer. Been slammed.

  6. Hi Dr. Ben! Just got blood work results today from a functional doctor. My vitamin D was 8.8. Homocysteine 20.4 with normal folic acid and B vitamins. I am 677TT (so is Mom) with rs2107301(T;T) and rs1544410(A;G).

    Have had escalating digestion, cognitive food sensitivities/allergies/asthma over the past year since I was hospitalized with pneumonia. So tired of being told to take another PPI/antibiotic/steroid…. or the dreaded “do you have anxiety?” I’m not my usual high energy self, so any thoughts or suggestions especially with how to get local traditional doctors on board would be great. What traditional specialty would be best suited to this?

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      Definitely sounds like you have a chronic infection with a high homocysteine and low vitamin D3.

      Normal folic acid – that doesn’t tell you much. Obviously it isn’t normal if your homocysteine is so high. And what form of folate are you taking? Consider HomocysteX Plus to help support your homocysteine levels.

      PPIs can also interfere with your D3 levels by increasing phosphate – and also lower your B12 which thus impacts many things including your homocysteine.

      Other things to consider:
      Liposomal curcumin to support inflammation – and utilize vitamin D as it stimulates VDR
      liposomal glutathione – as glutathione is low commonly in chronic infections

      Thoughts on how to get traditional doctors on board – wow. Tough. They are typically stuck in the ‘system’ even if they want to help you. Many times people bash doctors but it isn’t their fault. They went to medical school because they want to help. The issue is the insurance system sucks and they are locked in to their ‘standard of care’ which is crap.

      Good doctors are found at http://www.seekinghealth.org – directory; http://www.naturopathic.org – directory; http://www.functionalmedicine.org – directory

      1. Thank you so much for all the info, Dr. Ben. If I could make a suggestion, a YouTube video specifically for the patient to refer the doc to would be so helpful. Promise to give it a thumbs up if you make it!

        When you say infection, I’m in complete agreement. My working theory is the genetics are ground zero and after I had pneumonia all those meds triggered the metabolizing, toxins went up, stomach acid dropped, critters moved in, SIBO and inflammation along with malabsorbtion. Working on proving it and the blood work was a good start!

        Would be interested to know your thinking on heavy metal testing? Lead and mercury? Other metals? Blood, hair or urine test? I had mercury fillings taken out 10 years ago, lots of them that had been in for over 20 years and have never been tested but am seeing a lot of contradictory info.

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          Specifics on what you want to see in the video about doc / patient referral?

          Heavy metals – yes – absolutely. Unprovoked followed by provoked urinalysis. Doctors Data is great.

          1. I’m still working on foundation. Not sure if Vitamin D, also in combination with Mag, Cal and K2, does anything at all or makes it worse.
            I’m thinking on contacting a practicioner from your list to get me checked for infections. Is it advisable to finish foundational work first (money’s tight) or find a practicioner right now?
            Also, you mentioned what you think of heavy metal chelation in another comment. What’s your take on the cutler protocol? if you don’t approve, why not?

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            Hi Jens –

            Depends on how bad you are feeling and if you are happy with your momentum now. I get that money can be tight. Foundations are absolutely essential so focusing on those is a must or you are wasting your time and your health professional’s time – unless of course it is more emergent.

            Breathing is so important – and eating.

            I will be posting next month here – after my conference – some ABC’s of clean living/foundations.

            Cutler protocol – not sure. I first of all don’t believe in protocols. Secondly if he hasn’t updated it with all the new research coming out these days then it’s dated.

      2. Hi Dr. Ben! Can you PLEASE recommend, by name, a Southern California practitioner for MTHFR treatment and more? In other words, who would be your first go-to?

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          I am not familiar with this area well – there are a number of great docs in that area. I cannot refer by name unfortunately. We just had 300+ docs at my conference and many are impressive.

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      1. Thank you for the reply Dr Ben. My white cells always come in just under the min ref range, as do my platelets and have for years, not sure what the connection there might be. Don’t have any issues with CRP or anything autoimmune related, all good there.

        I only just had my 1,25 done and it was elevated, not crazy high, but it was out according to stuff I have read when compared to my 25 levels.

        I will start to look for infections, wonder if I have been walking around the past god knows how many years with un-diagnosed infections.

        Still learning every day, thank you. 🙂

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          Hi Dave –

          Hard to say – low WBC’s – I was too for years. I helped resolve them I believe by taking folinic acid and sleeping better and eating better. Folinic acid is they key though I believe. Low platelets is also tied to folinic acid.

          Inflammation can drive 1,25 Vitamin D3 levels.

          Checking infections is a must – most of us have one or two that are using our nutrient machinery and making us ill.

          Liposomal curcumin is supposed to support VDR based on research I read today. Stimulates VDR and reduces inflammation – good combo.

          1. Interesting about your low WBC and seemed to correct with folinic acid, sleep & diet. Also interesting about the connection with platelets & folinic acid too. Excuse my lack of knowledge here, but if I am already taking 5mthf, should that be having the same effect on WBC and Platelets as folinic acid?

            I think I will bite the bullet and take a look for infections, I have a root canal and know they can be a source of nasty stuff. Inflammation from my hip could also explain higher 1,25, could be a number of things going on. But with low WBC higher 1,25, should take the time to take a look like you said.

            I will look into the Liposomal curcumin thank you. 😉

  7. I’d love to hear your take on the Marshall protocol, limiting all vitamin D, that works for some people, but many doctors consider it dangerous. How does this all fit together?

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      I’m not an expert on the vitamin D3 and chronic infections. I am familiar with this protocol – some aspects of it. I will say that many times there is a response by our body that is happening and we don’t understand it so we try to push past it. Since 90% of our vitamin D comes from the sun and 10% only from food, and most of us live in non-sunny spots, then it seems that there should be a period of time when we become naturally vitamin D deficient? I’m theorizing here. Being vitamin D deficient for a short time is likely not an issue. The body will also sequester zinc and iron during infections to prevent the pathogens from getting them – and also methylation as well.

      1. I’d be really interested to see the data or information you’re using to come to this conclusion of infections hijacking our usage of vitamin D. What pathways are they interrupting to do this? What’s the mechanism? How exactly are they doing this, and how have they evolved to this adaptation – do you have any more info you could share?

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          It’s all in the research – just have to know how to dig it up and how to search for it.

          “Interestingly, microorganism infection can disable or hijack the VDR signaling. A number of species have been shown to downregulate the activity of VDR [49]. Borrelia burgdorferi can reduce VDR expression by 50 times in monocytes [49]. The caspases are upregulated by Shigella infection that limits the ability of VDR to perform gene transcription [50]. We demonstrated that commensal and pathogenic bacteria directly regulate colonic epithelial VDR expression and location [27]. VDR expression is higher in the proximal colon than in the distal colon, which is correlated with bacterial density and growth [27]. However, the role of vitamin D/VDR in regulating gut flora in tumorigenesis remains unknown.

          Vitamin D/VDR regulate response to intestinal immune responses, anti-inflammation, and cancer prevention. VDR dysfunction causes a decline in innate immune function and increases susceptibility to additional infections that contribute to inflammation progression. Hence, it is important to evaluate the associations among VDR, bacterial infection, and colitis-associated colon cancer.”

          https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693087/

          One of MANY papers…

  8. I’d love to hear your take on the Marshall protocol, limiting all vitamin D, that works for some people, but many doctors consider it dangerous. How does this all fit together?

  9. Dr Lynch, this is very important information and since using Strategene I recommend bith types of Vit D tests.
    The problem with the long list of pathogenic tests is the possible caveats in each.
    The Lyme test alone for example, if this is run at the wrong time, it won’t show up. Same for parasitic stool tests.
    Are you able to supoly a more specific list of labs that provide the best overall sweep?

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      Absolutely right. It is beyond the scope of this article. It is more of a FYI to get people thinking that a ‘normal’ vitamin D is not normal.

      Which labs to order and how to interpret is vastly more complex.

      I do plan on doing an interview with Dr Lesley Fein and hopefully we’ll get to some solid information.

  10. Dr Lynch, this is very important information and since using Strategene I recommend bith types of Vit D tests.
    The problem with the long list of pathogenic tests is the possible caveats in each.
    The Lyme test alone for example, if this is run at the wrong time, it won’t show up. Same for parasitic stool tests.
    Are you able to supoly a more specific list of labs that provide the best overall sweep?

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  11. I know I have infections. One is the Ebstein Barr virus. The trick is how do I get rid of it. It just keeps coming back.

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      Don’t shoot the messenger but EBV will keep coming back unless you strengthen yourself through proper diet, lifestyle, mindset, true restorative sleep, loving life and nurturing your microbiome, vitamin A, digestive function.

  12. I know I have infections. One is the Ebstein Barr virus. The trick is how do I get rid of it. It just keeps coming back.

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      yes – absolutely. Your body is trying to compensate for the infection – but it is leading to issues as well. Stopping vitamin D3 supplementation while combating the pathogen is likely needed.

  13. I have chronic Lyme and coinfections of mycoplasma and chlamydia pnemoniae as well as interstitial cystitis. I also have the vitamin D mutation as well as Heterozygous for MTHFR. My D3 has traditionally been on the low side but I am now supplementing.
    I don’t think my doctor ever heard of this test. Where do I find info for it ?

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      Any standard lab company has it – very common – just not commonly ordered.

      Likely your 25 OH vitamin D3 is low but your 1,25 OH Vitamin D3 is high.

      Need to determine if you feel better – or worse – by taking vitamin D. Many times people feel worse from it when having a chronic infection.

  14. Any standard lab company has it – very common – just not commonly ordered.

    Likely your 25 OH vitamin D3 is low but your 1,25 OH Vitamin D3 is high.

    Need to determine if you feel better – or worse – by taking vitamin D. Many times people feel worse from it when having a chronic infection.

  15. Search for infections and then what?? 20 years in and every avenue explored and no improvements only worse! What are we supposed to do to get these infections undercontrol?? antibiotics ohno….theyre terrible natural stuff hasnt worked.

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  16. Search for infections and then what?? 20 years in and every avenue explored and no improvements only worse! What are we supposed to do to get these infections undercontrol?? antibiotics ohno….theyre terrible natural stuff hasnt worked.

  17. Depends on presence of chronic infection or not. I am learning that one should reduce vitamin D during a chronic infection as it works better to kill it this way. Learning this from Shawn Bean and Lesley Fein, MD. I’ve a ways to go yet. Basing vitamin D supplementation on a SNP is not advisable.

  18. Definitely sounds like you have a chronic infection with a high homocysteine and low vitamin D3.

    Normal folic acid – that doesn’t tell you much. Obviously it isn’t normal if your homocysteine is so high. And what form of folate are you taking? Consider HomocysteX Plus to help support your homocysteine levels.

    PPIs can also interfere with your D3 levels by increasing phosphate – and also lower your B12 which thus impacts many things including your homocysteine.

    Other things to consider:
    Liposomal curcumin to support inflammation – and utilize vitamin D as it stimulates VDR
    liposomal glutathione – as glutathione is low commonly in chronic infections

    Thoughts on how to get traditional doctors on board – wow. Tough. They are typically stuck in the ‘system’ even if they want to help you. Many times people bash doctors but it isn’t their fault. They went to medical school because they want to help. The issue is the insurance system sucks and they are locked in to their ‘standard of care’ which is crap.

    Good doctors are found at http://www.seekinghealth.org – directory; http://www.naturopathic.org – directory; http://www.functionalmedicine.org – directory

  19. Just was diagnosed with transverse myelitis. I recently moved from a non sunny state to Florida my depression healed now this. Autoimmune conditions run in my family my twin sister has MS but I was told I had unlikely chance of having anything and here we are. I’ve had many test my b12 was very low but they said nothing of my vit d should I have them run these test as well. FYI I’m getting better each day will hopefully be walking on my on soon.

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      Hi Sharisah – Florida is nice and sunny but also a haven for mold and pesticides/herbicides. Need to assess the environmental impact as well as infections.

    2. I had transverse myelitis 12 years ago and was told I would never walk again. I don’t walk well but am able to do a lot. Improvement has been slow but steady through the years. I did not realize this was a combination of toxin buildup and autoimmunity. Here are some of the things that have helped.
      Heal your gut. Last year we discovered a severe parasite problem and have been treating that with multiple courses of Alinia. This has done a lot to improve my health! You will need a knowledegable doctor if you suspect parasites.
      Good nutrition with lots of greens and vegetables, clean water and clean meat. No sugar!!!
      Exercise even if you don’t see results as it helps prevent lymph problems.
      Stay away from drugs. Colloidal silver and vitamin C can be your friends instead of antibiotics. Supplements can help a lot too.
      Keep researching and trying what you can. Be quick to discard anything that doesn’t help. Pray a lot and have a grateful attitude. Never give up! Never give in! Blessings as you recover!

  20. I have hypothyroidism, and vit d was 14. Prescribed 50,000iu weekly plus 2000 daily. I struggle daily with nuerology symptoms. Any correlation? Thoughts on vitamin d amount? My muscles feel super weak a lot then super sore. I assume its probably connected?

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      That’s a lot. Yes – likely connected. Have your doctor check your calcium levels and also your 1,25 OH Vitamin D3 and 25 OH D3. Plus infections.

  21. Thanks so much for mentioning this. I have been on vitamin D supplements for a long while, but my levels just were not coming up.

    Recently, I had my TSH go up and looked into thyroid issues. I saw information by Izabella Wentz and took her class. Reading her new book Hashimoto’s Protocol would probably have done it also. At any rate, she went through diet (already I was doing that), supplements, (doing that too), but finally we got to infections and I realized I hadn’t ever tried to take something to get rid of bugs.

    When I was in 4th grade I had the second worst case of chicken pox that my soon-to-retire doctor had ever seen. I knew that chickenpox can later come out in Shingles. When I was 19, I mysteriously developed mononucleosis and after that pleurisy. Pleurisy was something that only was supposed to happen to old ladies or those with compromised immune systems so my doctor was confounded.

    In what I studied recently, I learned that 95% of people with thyroid issues have Epstein-Barr virus in their thyroid. I recalled after mono that I had sensitivities to cigarette smoke, perfumes, and chlorine pools. Some bloating also began to be noticeable after that illness. More frequent than in the past, because I remember having episodes where I looked pregnant as early as when I was 10- years-old. Now, I knew I was on to something. I began to use herbal treatments for viral infection. I felt extreme fatigue when I took too much. I think I am on to something, as I have dropped 12 pounds and my bloat seems to be going down AT LAST.

    One key part to my program seems to be starving the virus. To do that, I used grass fed meats and leafy greens, bites of fruit instead of any large quantities, and that seemed to avoid eating foods that I was allergic to. Years of undiagnosed celiac and taking supplements had probably fed the viruses quite well. Starving them with diet alone (in retrospect wasn’t enough), so after learning that viruses were my likely root cause I am going after them with natural anti-virals and NAET energy treatments.

    One time I starved my pests for several months with diet. My swelling and weight went down and the bloat went away. My energy levels also went up and I felt GREAT! However, when I added good foods back in, such as chicken, almonds, and other fruits and vegetables the swelling went up again. The bloating came back.

    I saw an article recently that bloating tummy may mean the chickenpox virus is still living in your gut. This rather confirmed my theories.

    I asked to know if people with the MTHFR have trouble getting rid of these viruses, do you have an answer for me, Dr. Ben Lynch?

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      MTHFR may impact your methylation which does impact your immune system – T cell formation. Yes. But – it is always more complex than that as you know.

  22. In addition, I have also been using water treated with light. Halo brand, I believe is who makes the lights for these treatments. They have treatments for Epstein-Barr, herpes, mold (I think?), and yeast. There are many other things the water can be treated to help. This seems to be making a big difference to me, although I don’t understand how.

  23. I am suffering from chronic bladder infections (histamine related). My vitamin D level is always low. I have VDR mutations and many others….I tried to supplement but after a week of taking vit D my bladder starts being on fire. My urologist doesn’t believe me saying that they use high doses of vit D to treat bladder infections. He recommended to try different forms. Now I am taking Seeking health drops (as they are free from additives). Does it mean that there is no point supplementing until I get rid of the infection? Does vit D trigger the infection in my case? Sorry I got confused…

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      It is confusing Elena. You’re not alone. I’m still not clear on the whole D picture either. It seems that vitamin D does aggravate some individuals and others it is amazing and life changing. Looking at the ratio of vitamin D is important – and sussing out infections. I didn’t learn about the significance of chronic infections until 2013. I keep harping on them every time I get the chance – they’re important to suss out. Food intolerances are big with interstitial cystitis. Quercetin, bromelain can be a game changer – plus avoiding histamine containing foods. If a urinalysis doesn’t show an infection, it may be food related. Something like HistaminX could be very helpful for a reactive bladder if histamine related.

      1. Dear Dr Lynch

        Thank you very much for your reply! Indeed quercetin helps a lot (even though it took a while for my body to accept it, I had to start with a very low dose and then gradually to increase it). I also take Daosin but will have a look at the one you mentioned. Thank you again, it is amazing that the doctor of your level can actually response to messages… thank you! your work is so important for us….desperately waiting for the book

  24. I recently upped my intake due to respiratory infection. A 30 yr mess of Lyme, EBV, and other infections, a sinus injury(from an unskilled surgeon) and associated tooth root have gone into full inflammation. Will ask my ND for this test. Do most ND’s know this? She graduated from Bastyr.

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  25. I have vit.D receptor mutation (VDR Taq +/+) and low vit. D in serum. Should I supplement vit. D? I take 4000 I.U. daily but not sure about it.

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      Need to suss out your labs – 25 and 1,25 Vitamin D3. Can’t tell from a SNP if you need a supplement or not.

        1. When can we get the info out that a SNP does not necessarily mean you will have a problem…don’t buy into the crap that a snp is a problem and something wrong with you.

          We seem to be doing just fine in Okinawa, and I’m sure we haven’t all won the genetic lottery. One thing is for sure- obsessing about health does not = health. That goes for those who are already “healthy” too. You can try and science the shit out of health.. unfortunately I don’t think it will get anyone any further ahead. The fundamentals are simple and effective.. and thoughts are huge.

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          Hi Brita –

          How do you know if your VDR is or isn’t working properly? A SNP? Those are really unknown how they alter D metabolism and physiology. Research is all over the place on it.

  26. I have vit.D receptor mutation (VDR Taq / ) and low vit. D in serum. Should I supplement vit. D? I take 4000 I.U. daily but not sure about it.

  27. Dr Lynch, curious on thoughts on Rife therapy with frequencies for killing bacteria and parasites for Lyme. I just attended a workshop claiming it was one of many ways to speed up healing.

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  28. My stored Vit D is consistently low, but my active Vit D was almost triple the lab high end range. My calcium is normal range. No doctors seems to know why and don’t appear it’s a big deal. I just had an ultrasound of my thyroid/parathyroid this morning. I’ve researched and thought maybe a parathyroid tumor. I’m just at a lost. I know I need Vit D, but can’t take it with this going on.
    I am working with a natural doctor that is treating for viruses too. Keeping fingers crossed that will make a difference after reading your information. Thank you for your dedication in helping unravel all these mysteries!

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      Sounds like infections. Don’t forget to suss out mold as well. Check your home, car, work, everywhere for mold – it’s everywhere.

  29. I have low storage D levels even with supplemental d3, but have never had the active Vit D checked. I have graves, ache in my joints, getting over plantar fasciitis, and am a severe insomniac , also can’t handle any stress, anxiety and hives all over! Does this signal infection, or B12 issues?? I am especially worried about insomnia because I just can’t function like this much longer. Any help would be appreciated! Thanks for all you do Dr. Lynch!

  30. I have low storage D levels even with supplemental d3, but have never had the active Vit D checked. I have graves, ache in my joints, getting over plantar fasciitis, and am a severe insomniac , also can’t handle any stress, anxiety and hives all over! Does this signal infection, or B12 issues?? I am especially worried about insomnia because I just can’t function like this much longer. Any help would be appreciated! Thanks for all you do Dr. Lynch!

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      Hi Missy –

      I am not a LDN expert – not sure. I do know that it is an anti-inflammatory but that’s about it – and well tolerated by most.

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      DJ –

      It may. Testing 1,25 OH D3 is tricky business – needs to clot and then be frozen and shipped frozen. Has a half life of 2 hours only.

      Low 25 OH doesnt really tell you anything – because that is the free vitamin D3 level. Most D3 is bound to binding proteins. Some people have higher numbers of binding proteins than others – and also pregnancy drives binding proteins higher as well which lowers their 25 OH.

  31. My experience: I went from 96 ng/mL (25-Hydroxy) to 61 96 ng/mL (25-Hydroxy) within the space of 8 weeks. During that time, I had shingles! It took about 2 months to bring my levels over 100 ng/mL (25-Hydroxy).

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  32. My experience: I went from 96 ng/mL (25-Hydroxy) to 61 96 ng/mL (25-Hydroxy) within the space of 8 weeks. During that time, I had shingles! It took about 2 months to bring my levels over 100 ng/mL (25-Hydroxy).

  33. Interesting about your work on Vita D and infections. I was very healthy until I developed a bad flu, that turned into extreme fatigue, infection of my diverticula and suspected yeast overgrowth after being on antibiotic therapy. I am positive for MTHFR heterozygous and my Vita D level is low. I have taken vita D all my life but since I have been sick (going on 10 months with fatigue) I cannot tolerate Vita D as my tinnitus goes crazy and anxiety worsens. My D level was 75 and now 30. Taking your methylation class now as I am stuck with this debilitating fatigue and need to get going back to my normal life. Was told this is a reoccurrence of mono and at 54 its debilitating. Changed my diet and energy improved. Cant tolerate antivirals at all and when I take supplements it has to be literally crumbs to start. Thanks for all your work. Little by little I am learning. I do go to a functional MD and we are working together and trying to learn together. I am a nurse practitioner who totally believes in your work and get raised eyebrows by the conventional medical community.

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      Hi Jill – glad you are fighting your way back. You’ll get there. Sauna? Electrolytes? Prolonged feeding – ie fasting at least 12 hours each night? 7 pm stop eating and 7 am earliest refeeding. Fasting like this is easy and well tolerated. Electrolytes too are key. Keep focusing on basics – they are key. Breathing….

  34. You recently featured an expert on Vit D that explained how white blood cells send out sort of like an antenae seeking nearby vit d. If none found then coils back up and doesnt activate. What I am reading here now seems contradictory in terms of whether D is needed to fight infection or just the opposite.

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      Hi Shannon –

      I will be the first to admit that my views on things change based on what is most accurate and current. I will never stay stagnant.

      D is absolutely needed to fight infections – absolutely. But your VDR gene has to be able to function – that is the vitamin D’s target. That’s my point. It’s not easy. Lot of different scenarios.

  35. You recently featured an expert on Vit D that explained how white blood cells send out sort of like an antenae seeking nearby vit d. If none found then coils back up and doesnt activate. What I am reading here now seems contradictory in terms of whether D is needed to fight infection or just the opposite.

  36. A Dexiscan I had about five years ago showed that I had osteoporosis in my spine. Thanks to Dr. Susan Brown’s website – The center for Better Bones – I found that I should have some specific blood tests including PTH. I had to insist that these tests be done. The PTH came back high and my Vitamin D level ( 25 OH ) was 33. I was sent to an endocrinologist who said 33 was too low. He said I had secondary hyperparathyroidism. He put me on 2000 IU D3 ( now 5,000 ) and 1200 Calcium beyond what I was getting through my diet. My vitamin D levels got higher, but did not reach 60 until my dermatologist told me to take Vitamin K. I take a Super K supplement.
    My endocrinologist has never measured my 1.25 OH. In fact I am wondering the validity of any normal PTH reading I ever had because a fasting Genova Nutrval blood test done in September of 2016 showed my PTH high with a 76.8 level. A week later my endocrinologist did his usual non-fasting blood test and it showed a normal level of 48.
    I am thinking the 25 OH is not providing a complete picture of my condition.
    I have done my StrateGene report and I have hetero MTHFR A1298C
    Genetic Genie showed I had homozygous VDR, but StrateGene showed Ancestral. I am currently being treated for leaky gut by a doctor within the Seeking Health directory.
    Should I insist on the 1.25 OH test? If they dismiss my concerns I can go back to my Functional Practitioner who did the Nutrval testing.

    1. Post
      Author

      Hi Diane –

      Seems like they are missing something to me. I am discussing Vitamin D in two presentations this coming week. https://seekinghealth.org/product/sheicon2017-livestream-recording

      I am presenting a brand new vitamin D planner which is amazing. Really shows how D levels can be impacted by lifestyle, diet, pathogens, inflammation, etc

      So even if you order a 1,25 OH – first of all – will they do it right and secondly – will they know what to do. I am still learning but what I do know is D physiology is very complex. Thankfully my D planner is simplifying it and showing some really cool patterns.

      I highly recommend you consider tuning in for those two talks at least –

      1. Thank you for your reply. I saw my doctor last Monday and she agreed to test the 1,25 OH. She put in orders at the hospital lab. I think I will wait to do my fasting test until after I see your presentations. Going from your reply to DJ about the correct method of testing 1,25 OH, I don’t hold much hope that the hospital will take the time to do it right. But I will ask them questions before they draw the blood. I know I can take your information to my Functional Practitioner. She is wonderful, but her clinic is two hours away from my home.

  37. A Dexiscan I had about five years ago showed that I had osteoporosis in my spine. Thanks to Dr. Susan Brown’s website – The center for Better Bones – I found that I should have some specific blood tests including PTH. I had to insist that these tests be done. The PTH came back high and my Vitamin D level ( 25 OH ) was 33. I was sent to an endocrinologist who said 33 was too low. He said I had secondary hyperparathyroidism. He put me on 2000 IU D3 ( now 5,000 ) and 1200 Calcium beyond what I was getting through my diet. My vitamin D levels got higher, but did not reach 60 until my dermatologist told me to take Vitamin K. I take a Super K supplement.
    My endocrinologist has never measured my 1.25 OH. In fact I am wondering the validity of any normal PTH reading I ever had because a fasting Genova Nutrval blood test done in September of 2016 showed my PTH high with a 76.8 level. A week later my endocrinologist did his usual non-fasting blood test and it showed a normal level of 48.
    I am thinking the 25 OH is not providing a complete picture of my condition.
    I have done my StrateGene report and I have hetero MTHFR A1298C
    Genetic Genie showed I had homozygous VDR, but StrateGene showed Ancestral. I am currently being treated for leaky gut by a doctor within the Seeking Health directory.
    Should I insist on the 1.25 OH test? If they dismiss my concerns I can go back to my Functional Practitioner who did the Nutrval testing.

  38. Do you know if the body still can utilize vitamin D for bone building together with the other fat soluble vitamins and minerals, – if the vitamin D-gene is blocked or inhibited by chronic infections? Or is the bone building function of vitamin D dependent on the function of the gene?

    1. Post
      Author
  39. I also wonder how careful you should be with improving methylation if you have borrelia or mycoplasma, if the Main reason for your undermethylation are environmental toxins and not the infections themselves?

    1. Post
      Author

      One has to be quite careful. I am not a fan of hitting methylation first. Supporting with electrolytes, fundamentals and fighting the infections are important first steps.

  40. Hi Dr. Ben – I just ran across this article while looking for more info on Vit-D. My FM doc here in Queen Creek AZ has introduced me to the Coimbra protocol for Vitamin D as used by him to treat autoimmune disorders like MS – I was already doing most of the aspects of the protocol but found the Vitamin D information very supportive. Dr. Jensen spent some time in Brazil with Dr. Coimbra and has used his new skill-set to help get me on the right track with possible problems of hypercalcemia by using 4 daily doses of B2 PRP and Mg Cl while suspending the D for a couple of weeks to see if the CA changed. Now I have restarted the D at 16 mg/day for maintenance. Thought you might be interested in http://www.vitamindprotocol.com/dr.-coimbra-s-ms-protocol.html

  41. Good Morning Dr. Lynch

    I’m Daniele from Italy suffering from small fiber neurophathy after hepathytis B vaccination 16 years ago.
    I managed all my infections but my situation is still low Vitamin D (25Oh) and high Vitamin D (1,25).
    I read all about marshall protocoll but I’m very contrary about his plan theraphy.
    What do you suggest in this situation ? Is it smart to take Vitamin D supplements ? I’m also assuming your liposomal curcumin as tou suggested…

    Thanks a lot

    Daniele

    1. Hi Daniele –

      Sorry you are struggling with this. I’d look also at liposomal glutathione, carnitine and liposomal curcumin. Benfothiamine could also be of use along with alpha R lipoic acid.

      I would also highly consider watching my lectures on vitamin D – available on the SHEICON 2017 course.

      Right now it is 40% off using code 40OFF – expires Sept 24.

      There are other triggers for this imbalanced D ratio.

  42. Thanks a lot Dr Lynch,

    I forgot to telle you that from your StrateGene I have

    – MAOB rs1799836 (+/+*, C)
    – VDR Fok1 (+/+, GG)

    so should I avoid your liposomal curcumin ?

    Why should I take vitamin D if I have a very high ratio vit D 1,125 OH / Vit D 25 OH ?

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